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Microplate Reader

Microplate Reader

Introducing our highly advanced Microplate Reader, designed specifically for medical professionals. This state-of-the-art device is equipped with advanced optical technology, enabling precise and accurate measurements of samples in microplates. With its user-friendly interface and intuitive software, it offers effortless operation and seamless data analysis. The Microplate Reader is capable of reading multiple assays simultaneously, making it an essential tool for high-throughput screening and diagnostic applications. Trust in the reliability and performance of our Microplate Reader, and elevate the precision of your medical research and diagnostic testing.
  • Applications

    • Cell Viability and Proliferation Assays: Microplate readers are often used to assess cell viability and proliferation using colorimetric or fluorometric assays such as MTT, XTT, or resazurin assays. These assays measure metabolic activity or cell viability based on the conversion of a substrate into a colored or fluorescent product.
    • Enzyme Activity Assays: Microplate readers are used to measure enzyme activity by monitoring the production or consumption of a substrate or product. Enzyme assays such as ELISA (enzyme-linked immunosorbent assay) are widely performed in microplate format for applications including cytokine detection, hormone quantification, and protein-protein interaction studies.
    • Gene Expression Analysis: Microplate readers equipped with fluorescence detection capabilities are commonly used in gene expression analysis techniques such as qPCR (quantitative polymerase chain reaction) and RT-PCR (reverse transcription polymerase chain reaction). These assays allow researchers to quantify gene expression levels in a high-throughput manner.
    • Reporter Gene Assays: Microplate readers are used in reporter gene assays to study gene regulation and promoter activity. Fluorescent or luminescent reporter genes such as luciferase or green fluorescent protein (GFP) are commonly used to monitor transcriptional activity or protein expression levels in response to different stimuli.
    • Drug Screening and Pharmacology: Microplate readers are essential tools in drug discovery and pharmacology for high-throughput screening of compound libraries. They are used to measure various parameters such as enzyme inhibition, receptor binding, and cell signaling pathways using fluorescence, luminescence, or absorbance-based assays.
    • Protein-Protein Interaction Studies: Microplate readers equipped with fluorescence resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) capabilities are used to study protein-protein interactions and protein conformational changes. These techniques enable researchers to monitor biomolecular interactions in a microplate format.
    • Toxicity and Drug Safety Assessment: Microplate readers are used in toxicology studies to assess the cytotoxicity and genotoxicity of chemical compounds. Cell-based assays such as the lactate dehydrogenase (LDH) release assay and the comet assay can be performed in microplates to evaluate the effects of toxins or drugs on cell viability and DNA damage.
    • Metabolomics and Metabolic Profiling: Microplate readers are used in metabolomics research to analyze metabolic pathways and metabolic profiles. Assays such as ATP quantification, NAD(P)H/NAD(P)+ ratio measurement, and glucose uptake assays can be performed in microplates to study cellular metabolism and energy production.

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