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Inverted Microscopes

Inverted Microscopes

Introducing our state-of-the-art Inverted Microscope, designed to meet the specific needs of medical professionals and researchers. This advanced instrument allows for the examination of cells, tissues, and microorganisms with exceptional clarity and precision. With its inverted design, it is ideal for observing live biological specimens, making it an essential tool for cell culture analysis and in vitro fertilization procedures. The microscope is equipped with high-quality optics, advanced imaging software, and ergonomic features to ensure ease of use and accurate analysis. Whether used in medical labs, research facilities, or clinical settings, our Inverted Microscope sets the standard for reliable, high-performance microscopy.
  • Applications

    • Cell Culture Observation: Inverted microscopes are commonly used in cell culture laboratories for observing cells growing on the bottom of culture dishes or plates. Their design allows for easy manipulation of samples and provides a clear view of cells in their natural environment.
    • Live Cell Imaging: Live cell imaging, where cells are observed in real-time under controlled conditions, benefits greatly from inverted microscopes. Researchers can study cellular processes such as mitosis, migration, and cell-cell interactions with high clarity and minimal disturbance to the sample.
    • Microinjection and Micromanipulation: Inverted microscopes are essential tools for microinjection and micromanipulation techniques. Researchers can precisely inject substances such as drugs, DNA, or proteins into individual cells or manipulate cellular structures using microtools under the microscope's guidance.
    • Microbial Observation: In microbiology, inverted microscopes are used to observe microorganisms such as bacteria, yeast, and algae. The inverted design allows for easy examination of samples contained in petri dishes, culture flasks, or microfluidic chambers.
    • Embryology and Developmental Biology: In developmental biology, inverted microscopes play a crucial role in studying embryo development and organogenesis. Researchers can observe the growth and differentiation of embryos and tissues over time, providing insights into developmental processes.
    • Histology and Tissue Culture: Inverted microscopes are utilized in histology and tissue culture laboratories for examining thin tissue sections and cultured cells. They enable researchers to study tissue morphology, cell structure, and interactions within tissues.
    • Material Science and Metallurgy: Inverted microscopes are also used in material science and metallurgy for examining opaque samples such as metals, ceramics, and polymers. With specialized contrast techniques such as darkfield and polarized light microscopy, researchers can analyze material properties and structures at a microscopic level.
    • In Vitro Fertilization (IVF) and Assisted Reproductive Technologies (ART): In reproductive medicine, inverted microscopes are used in procedures like IVF and intracytoplasmic sperm injection (ICSI). Clinicians can select healthy sperm and embryos for implantation based on their morphology and viability observed under the microscope.
  • Ease of Use

    The Graphical Experimental Manager (GEM) of cellSens Dimension software offers fully automated multidimensional observation (X, Y, Z, T, wavelength, and positions) and eases experiment setup. To increase efficiency, you can define macro functions, such as executing deconvolution processing, in the GEM. 

  • Precise, Reliable Hardware

    • Automated Focusing: The cellSens software’s multipoint focus map enables automated focusing across wide image areas with multiple objective lenses, making it easier to stay in focus while you navigate your samples.
    • Bright, Uniform Fluorescence Illumination: The fluorescence illuminator incorporates a fly-eye lens system to distribute light evenly. The system provides bright and uniform illumination to the entire field of view, which is well-suited for image stitching applications.

  • Well Plates Made Simple

    The Well Plate Navigator and Database solutions for cellSens software facilitate proper screening during an experiment. Together, they improve the efficiency of viewing and analyzing well plate images with a large amount of data.

    Information such as date, file name, or well plate number are easily selectable with icons, displaying any selection of captured images to be used for further analysis. These solutions also enable continuous analysis of selected images (the batch macro function) using the well plate GUI.

  • Rapid Deconvolution

    Olympus cellSens Dimension software includes live 2D deblurring for preview and acquisition, enabling better focusing of thick specimens. For further detail enhancement, TruSight deconvolution is available to reassign out-of-focus light. TruSight uses a constrained iterative deconvolution algorithm to produce improved resolution, contrast, and dynamic range with industry-leading high speed through GPU processing. To improve experiment efficiency, deconvolution processing can be defined as a macro function in the GEM.

  • Advanced Analysis

    Images can be easily converted to statistically relevant data with cellSens software. The software features region-of-interest, phase analysis, and cell counting capabilities.

  • Simplify Your Workflow

    Suitable Objectives for Observation with Plastic Vessels: The objectives enable high-resolution observation of the cell proliferation process and deliver improved contrast across a wide area. This gives you the flexibility to image through plastic-bottom dishes in addition to glass.

  • Specifications

    Observation Method Super Resolution   -
      Confocal   -
      Total Internal Reflection Fluorescence   -
      Fluorescence (Blue/Green Excitation)  
      Fluorescence (Ultraviolet Excitation)  
      Differential Interference Contrast (DIC)  
      Phase Contrast  
    Revolving Nosepiece Motorized (6 position)  
    Focus Motorized  
      Z Drift Compensator  
    Observation Tubes Widefield (FN 22) Tilting Binocular
    Illuminator Transmitted Köhler Illuminator LED Lamp
        100 W Halogen Lamp
      Fluorescence Illuminator 100 W Mercury Lamp
        Light Guide Illumination
    Fluorescence Mirror Turret Motorized (8 position)  
    Stage Motorized  

    Contact your local sales representative to hear about motorized stage options

      Mechanical Mechanical Stage with Right Handle
    • X: 114 mm, Y: 75 mm
        Mechanical Stage with Left Short Handle
    • X: 114 mm, Y: 75 mm
    Condenser Motorized Universal Condenser W.D. 27 mm, NA 0.55, motorized aperture and polarizer
      Manual Universal Condenser NA 0.55/ W.D. 27 mm
        Ultra-Long Working Distance Condenser NA 0.3/ W.D. 73.3 mm
    Confocal Scanner    


    Super Resolution Processing    




    Dimensions (W × D × H)     323 (W) x 475 (D) x 706 (H) mm (IX83 microscope frame)
    Weight     Approx. 47kg

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